Search Results - Research Tools - Membrane receptors

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Human Thyrotrophin Receptor Monoclonal Antibody - Clone 2C11
The human thyrotrophin receptor (TSHR) is found primarily in epithelial cells of thyroid follicles where it induces (by cAMP) the phospholipase C and protein kinase A signal transduction pathways. TSHR is the major pathogenic autoantigen in human autoimmune thyroid Graves’ disease.LanesTSHRGlycosylated TSHRTSHR - GSTResidues 125-369 TSHR - ...
Published: 14/04/2010   |   Inventor(s): Philip Shepherd
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Category(s): Research Tools - Membrane receptors
Human Thyrotrophin Receptor Monoclonal Antibody - Clone 4C1
Research tool forWestern blottingImmunoprecipitationFlow cytometryImmunohistochemistry (frozen section)Inhibits binding of TSH to TSH receptor by 70-80%.The human thyrotrophin receptor (TSHR) is found primarily in epithelial cells of thyroid follicles where it induces (by cAMP) the phospholipase C and protein kinase A signal transduction pathways. ...
Published: 14/04/2010   |   Inventor(s): Philip Shepherd, Alan Johnstone
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Category(s): Research Tools - Membrane receptors
Human Thyrotrophin Receptor Monoclonal Antibody - Clone 3B12
Research tool for:Immunoblotting Immunoprecipitation Flow cytometry Immunohistochemistry (frozen section)Product TypeHybridoma for monoclonal antibodyImmunogenBacterially expressed extracellular domain (residues 1-415) of human TSHR fused to GSTCross ReactivityCross-reacts with human and theoretically with rat, pig, sheep, mouse, dog, catSpecificit...
Published: 14/04/2010   |   Inventor(s): Philip Shepherd
Keywords(s):  
Category(s): Research Tools - Membrane receptors