HIV-1 p17 Gag monoclonal antibody - Clone 17-3

Reagent Name

HIV-1 p17 Gag monoclonal antibody (#17-3)

Description

Hybridoma expressing antibodies to human immunodeficiency virus type 1

Immunogen

Bacterially expressed, hexahistidine amino-terminal tagged HIV-1 p17 Gag protein (clade B, HXB-3 isolate)

Relevance

p17 is encoded by the HIV gag gene and is an important structural component of the HIV particle

Cross reactivity

Not tested

Specificity

Epitope not mapped

Tested applications

Western blots for clade B isolates of HIV; immunoprecipitation assays; immunofluorescence/FACS assays

Raised in

Mouse

Clonality

Monoclonal

Isotype

IgG_{2b, k}

References

1. Fouchier RA, Meyer BE, Simon JH, Fischer U, Malim MH. HIV-1 infection of non-dividing cells: evidence that the amino-terminal basic region of the viral matrix protein is important for Gag processing but not for post-entry nuclear import. EMBO J 16:4531-4539, 1997.
2. Gaddis NC, Chertova E, Sheehy AM, Henderson LE, Malim MH. Comprehensive investigation of the molecular defect in vif-deficient human immunodeficiency virus type 1 virions. Journal of Virology 77:5810-5820, 2003.