Mouse anti-human Talin antibody - Clone TA205

Reagent Name

Mouse anti-human Talin antibody

 

Immunogen

Human platelet talin.

 

Relevance

Talin is a cytoskeletal protein that is found concentrated in focal adhesions. It is capable of linking integrins to the actin cytoskeleton either directly or indirectly by interacting with vinculin and alpha-actinin

 

Cross reactivity

TA205 immunoblots a 225 kDa protein in human platelet lysates

 

Specificity

Epitope resides in region 139-433 in talin.

 

Tested Applications

Immunohistochemistry, Western blotting and immunoprecipitation.

 

Raised in

Mouse

 

Clonality

Monoclonal

 

Isotype

IgG1

 

References

  1. Porter RM et al. (1993) J Pathol.; 170: 435-40. Bolton SJ et al. (1997) Cell Motil. Cytoskeleton 36, 363-376.
Patent Information:
For Information, Contact:
Salma Ishaq
IP & Licensing Manager
King's College London
salma.ishaq@kcl.ac.uk
Inventors:
Kalwant Authi
Michael Wilkinson
Keywords: