Search Results - kalwant+authi

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Mouse anti-human actin antibody - Clone MM2/193

Reagent NameMouse anti-human actin antibodyImmunogenHuman platelet membranes.RelevanceActin is a major protein found in most cells and is important in cell motility and contraction. It is a major component of the cytoskeleton. Cross reactivityRecognises human actin as a 42-47 kDa protein in platelet lysates.SpecificityEpitope is not mapped.Tested ApplicationsWestern...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Structural proteins

Mouse anti- human filamin antibody - Clone PM6/317

Reagent NameMouse anti- human filamin antibodyImmunogenHuman platelet membranesRelevanceFilamin (also called actin binding protein) is a structural protein that forms flexible cross-links between two actin filaments. Filamin is a homodimer of polypeptide chains each joined to the other at one end with an actin binding site. It is present in smooth muscle,...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Structural proteins

Mouse anti-human Integrin beta 3 (CD61) antibody - Clone PM6/13

Reagent NameHuman Integrin beta 3 antibodyImmunogenHuman platelet membranesRelevanceIntegrin beta 3 is also known as glycoprotein IIIa and in a complex with the integrin alpha 2b subunit forms the receptor for fibrinogen, fibronectin and von Willebrand Factor on activated platelets. Integrin beta 3 can also complex with alpha V integrin. The antibody...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Cell adhesion proteins

Mouse anti-human Vinculin antibody - Clone V284

Reagent NameMouse anti-human Vinculin antibodyImmunogenPurified human platelet vinculinRelevanceVinculin is a 117 kDa membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton.Cross reactivityHuman, rabbit, rat, chicken, mouse.SpecificityEpitope not mapped. Recognises...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Cell adhesion proteins

Mouse anti-human integrin alpha 2b (CD41) antibody - Clone PM6/248

Reagent NameMouse anti-human integrin alpha 2b (CD41) antibodyImmunogenHuman platelet membranesRelevanceIntegrin alpha 2b is also known as glycoprotein IIb and in a complex with the integrin beta 3 subunit forms the receptor for fibrinogen, fibronectin and von Willebrand Factor on activated platelets. The antibody activates platelets under stirring...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Cell adhesion proteins

Mouse Anti-T Cell / Neutrophil Marker Antibody - Clone RPN3/57

Reagent NameMouse Anti-T Cell / Neutrophil Marker AntibodyImmunogenRabbit peritoneal neutrophilsRelevanceUseful for the detection of rabbit neutrophils and T cellsCross reactivityNot testedSpecificityRecognises an antigen expressed strongly on neutrophils, thymocytes, a subset of T cells and platelets. Epitope not identified.Tested ApplicationsFlow...

Published: 12/12/2023 | Inventor(s): Kalwant Authi

Keywords(s):

Category(s): Research Tools - Lymphocyte signalling

Mouse anti-human SERCA 3 antibody - Clone PL/IM430

Reagent NameMouse anti-human SERCA 3 antibodyImmunogenHuman platelet intracellular membranesRelevanceSERCA 3 is the sarco-endoplasmic reticulum Ca2+ ATPase that sequesters Ca2+ into intracellular stores of mammalian cells. This antibody inhibits Ca2+ sequestration and Ca2+ATPase activity mediated by human SERCA3. Cross reactivityHuman SpecificityEpitope...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Transport and trafficking

Mouse anti-human Talin antibody - Clone TA205

Reagent NameMouse anti-human Talin antibodyImmunogenHuman platelet talin.RelevanceTalin is a cytoskeletal protein that is found concentrated in focal adhesions. It is capable of linking integrins to the actin cytoskeleton either directly or indirectly by interacting with vinculin and alpha-actininCross reactivityTA205 immunoblots a 225 kDa protein in...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Cell adhesion proteins

Mouse anti-human Glycoprotein 1b alpha (CD42b) antibody - Clone PM6/40.

Reagent NameMouse anti-human Glycoprotein 1b alpha antibodyImmunogenPlatelet membranesRelevanceGlycoprotein 1b (GP1b) is heavily expressed in platelets and megakaryocytes. It serves as a receptor for von Willebrand Factor and thrombin.Cross reactivityRecognises human GP1b, other species GP1b to be tested.SpecificityEpitope not mappedTested ApplicationsFlow...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Lymphocyte signalling

Mouse anti-human Glycoprotein 1b alpha (CD42b) antibody - Clone MM2/174.

Reagent NameMouse anti-human Glycoprotein 1b alpha (GP1b alpha subunit) antibodyImmunogenPlatelet membranesRelevanceGlycoprotein 1b is heavily expressed in platelets and megakaryocytes. It serves as a receptor for von Willebrandt Factor and thrombin.Cross reactivityRecognises human GP1b, other species to be tested.SpecificityEpitope not mapped.Tested...

Published: 12/12/2023 | Inventor(s): Kalwant Authi, John Michael Wilkinson

Keywords(s):

Category(s): Research Tools - Lymphocyte signalling